Wrinkle softening and smoothing treatments, often referred to as neuromodulators, are a popular non-invasive cosmetic treatment used to reduce and prevent the formation of wrinkles. 

Treatment Process

  • Non-Invasive: After a consultation with a medical professional, wrinkle softening and smoothing treatments are minimally invasive and typically involve a series of small treatments into specific muscles or areas of the face.
  • Preventative Measure: These treatments are often used as a preventive measure to soften and reduce the appearance of dynamic wrinkles, which are wrinkles that form as a result of facial expressions, such as smiling, frowning, or raising the eyebrows.
  • Additional Uses: In addition to addressing cosmetic concerns, wrinkle softening and smoothing treatments can also be used treat issues such as excessive sweating (hyperhidrosis) and jaw clenching or teeth grinding (bruxism) after a consultation with a medical professional.

Expected Results

The mechanism of action of wrinkle softening and smoothing treatments involves blocking the signals between nerves and muscles. Here’s what you can expect in terms of results:

  • Reduced Muscle Movement: By blocking the nerve signals to the treated muscles, wrinkle softening and smoothing treatments reduce muscle contractions and movement. This decreased muscle activity helps to prevent the formation and deepening of wrinkles and lines associated with facial expressions.
  • Softer and Fresher Appearance: As the muscles relax, the overlying skin also relaxes, resulting in a smoother and softer appearance. This can give the face a more refreshed and youthful look.
  • Dynamic vs. Static Wrinkles: Wrinkle softening and smoothing treatments are particularly effective against dynamic wrinkles, which are the wrinkles that appear when you make facial expressions. However, they may not be as effective for static wrinkles, which are visible even when the facial muscles are at rest. Static wrinkles often result from a loss of skin elasticity and collagen. Volume and Contouring treatments, a different type of cosmetic treatment, are typically used to address static wrinkles by adding volume beneath the skin.

It’s important to note that the longevity of the results can vary among individuals, and follow-up treatments are typically needed to maintain the effects. The specific areas and amount of product used will depend on individual goals and facial anatomy. Usually expect 3 months to 5 months duration of effect.

Procedure Overview

  • Procedure time: 15 minutes with consultation
  • Downtime Required: Avoid vigorous exercise for 24 – 48 hours, avoid putting any pressure or massage the treated area for at least 4 hours.
  • Results Duration: Lasting 3 to 5 months. Onset of action is approximately 2 weeks after your treatment.
  • Cost of Treatment : From $5 – $13.50 per unit


Wrinkle softening and smoothing treatments are commonly injected into the:

  • Frown
  • Forehead
  • Crows Feet (lines around the eyes)
  • Eyebrow lift
  • Bunny lines (nose)
  • Gummy smile
  • Chin dimpling 
  • TMJ (Masseter muscle) 
  • Neck 
  • Gummy smile 
  • Underarm sweating (hyperhidrosis)
  • Hayfever reduction nasal spray
  • Headaches
  • Chronic muscle pain

Pair this treatment with: Volume and Contouring Treatments, Collagen powders, Bio-Remodellers, Bio-Stimulators, Hydrafacial, Tixel and Cutera Laser.

Like to know more about your treatment options? Contact Sanctuary Cosmetic Clinics Australia on 02 9054 0887.


See All
  • Fat Dissolving Treatment

    Made from deoxycholic acid, fat dissolving treatments are injected under the chin to reduce the amount of fat.

    30 minutes
  • Mesotherapy Skin Boosters

    Skin boosters are injected to assist the skin in hydration, nourishment and rejuvenation.

    30 minutes
  • PRP Platelet-Rich Plasma Treatments

    Platlet Rich Plasma is an extract of your own blood that is spun and the platlets reinjected to form new collagen and elastin.

    60 minutes
  • Skin Laxity and Firmness Treatments

    Skin Laxity and Firmness injectable treatments rejuvenate skin by stimulating collagen, reducing wrinkles, and restoring volume.

    45 minutes
  • Threads

    A thread lift is a cosmetic procedure aimed at lifting and rejuvenating the skin, typically on the face, using specialised threads. 

    60 minutes
  • Volume and Contouring Treatments

    Volume and contouring treatments can be used to correct wrinkles and folds, restore volume loss, increase lip volume and enhance definition, sculpt and shape the natural contour of the face.

    45 minutes

Skin Treatments

See All
  • 4D RF Body Contouring

    The 4D RF uses a multipolar Radio Frequency and Pulse Electro Magnetics to produce heat under the skin to shrink the fat.

    30 minutes
  • AC Dual

    Explore the benefits of our AC Dual Treatment, utilizing Intense Pulsed Light to address acne concerns effectively, ensuring clearer and healthier-looking skin with reduced active acne.

    20 minutes
  • Acnelan

    The acnelan treatment is an intensive treatment for acne-prone skin to clear blocked pores, remove impuriites and improve skin texture.

    60 minutes

    A semi-permanent foundation that is microneedled into the skin.

    45 minutes
  • Chemical Peel

    A chemical peel can be used to treat concerns with the skin such as pigmentation, acne or skin texture.

    30 minutes
  • Cutera excelV+ Laser

    A laser treatment used to treat visible veins, discolouration and wrinkles.

    45 minutes

Search Sanctuary Cosmetic Clinics